皮膚用抗感染 Topical treatment of nail infections caused by a variety of fungi (onychomycosis)
藥理
Amorolfine is a morpholine derivative with antifungal activity. It appears to act by interfering with the synthesis of sterols essential for the functioning of fungal cell membranes.
藥動學
After topical application, systemic absorption of amorolfine is
negligible.
禁忌症
Hypersensitivity to amorolfine or to any of the excipients.
懷孕分類
Unknown, it should not be used during pregnancy and/or lactation unless clearly necessary.
哺乳分類
Unknown, it should not be used during pregnancy and/or lactation unless clearly necessary.
副作用
Skin irritation, presenting as erythema, pruritus, or a burning sensation, and, rarely, more severe skin reactions have been reported after topical application of amorolfine.
劑量和給藥方法
Painted onto the affected nail once or sometimes twice weekly until the nail has regenerated. Treatment generally needs to be continued for 6 to 12 months.
小兒調整劑量
No specific dosage recommendations
腎功能調整劑量
肝功能調整劑量
安定性
Protect from heat. Keep bottle tightly closed after use.