氣喘或慢性阻塞性肺病 Bronchospasm associated with COPD, asthma, bronchitis, and emphysema

Anticholinergic bronchodilator

Bioavailability: 2% to 7%
Protein binding: ~9%

1. Hypersensitivity
2.Caution in patients with acute narrow-angle glaucoma, prostatic hypertrophy, bladder-neck obstruction

B

Infant risk cannot be ruled out

Dryness, bitter or bad taste in the mouth, paradoxical deterioration in pulmonary function resulting in bronchoconstriction

Chronic obstructive pulmonary disease:
1. Acute exacerbation:
(1) For patients at home: 0.5 mg every 6 to 8 hours as needed
(2) For patients requiring emergency department or hospital-based care: 0.5 mg every 1 hour (up to 3 doses), then every 2 to 4 hours as needed
2. Intermittent symptom relief: 0.5 mg every 4 to 8 hours as needed
3. Maintenance (alternative agent): 0.5 mg every 6 to 8 hours
Acute asthma (exacerbations) (off-label use):
0.5 mg (500 mcg, one unit-dose vial) every 20 minutes for 3 doses, then as needed

Bronchospasm associated with chronic pulmonary conditions:
(Children ≥12 years and adolescents) 0.5 mg 3-4 times daily with doses 6-8 hours apart
Bronchospasm, wheezing:
(Limited data available) 0.125-0.25 mg every 4 hours
Acute asthma, exacerbations:
(Limited data available) 0.25-0.5 mg every 20 minutes for 1 hour, then as needed
Asthma, maintenance:
(Limited data available) 0.25-0.5 mg every 6 hours

There are no dosage adjustments provided in the manufacturer's labeling (has not been studied).

There are no dosage adjustments provided in the manufacturer's labeling (has not been studied).