Mupirocin is bacteriostatic at low concentrations and bactericidal at high concentrations. This agent reversibly and specifically binds to bacterial isoleucyl transfer RNA synthetase, thereby inhibiting bacterial protein and RNA synthesis. DNA synthesis and cell wall formation are affected to a lesser extent.
藥動學
禁忌症
Hypersensitivity to mupirocin or any components of the product
懷孕分類
B
哺乳分類
Infant risk cannot be ruled out
副作用
Dermatologic: Application site pain (1.5% ), Pruritus (1% ), Sensation of burning of skin (1.5% ), Stinging of skin (1.5% )
劑量和給藥方法
Apply 2% ointment topically 2-3 times per day for 3 to 5 days; reevaluate if no response (manufacturer dose).