for oral hygiene prior, during and after dental and oral surgery, e.g. after tonsillectomy and dental procedures.
適用於牙科與口腔手術之前、期間與之後（例如扁桃腺切除與牙科程序之後）的口腔衛生。
Povidone-Iodine Ph. Eur. 0.45% w/v.Povidone-Iodine is a complex of the polymer polyvinylpyrrolidone with iodine (Povidone-Iodine) which, after application, continues to deliver iodine over a period of time. Elemental iodine ( I2 ) has long been known as a highly effective microbicidal agent that rapidly kills bacteria, viruses, fungi and some protozoa in vitro. Two mechanisms are involved: free iodine rapidly causes microbial killing, whereas iodine bound to the polymer serves as a reservoir.
Absorption: In normal individuals, topical application results in very little systemic iodine absorption. This product is intended for local use to the mouth and throat. Iodine elimination is almost exclusively by renal route with a clearance of 15 to 60 ml plasma/min depending on serum iodine level and creatinine clearance.
Not to be used in known hypersensitivity to iodine or povidone or any other of the excipients listed at Pharmaceutical Particulars. Not to be used in hyperfunction of the thyroid (hyperthyroidism), other manifest thyroid diseases, as well as before and after radioiodine therapy for hyperthyroidism, until a lasting cure has been obtained. It should not be used for 4 weeks prior to radioiodine scintigraphy or radioiodine treatment of thyroid carcinoma. Patients with goiter, thyroid nodules, or other thyroid diseases (especially elderly patients) are at risk of developing thyroid hyperfunction (hyperthyroidism) from the administration of large amounts of iodine. Not to be used in patients on concurrent lithium therapy.Not to be used in children below 6 years of age.
C
本藥反覆使用可能造成孕婦及胎兒甲狀腺腫及甲狀腺功能低下。<20221212>Avoided
反覆使用可能導致嬰兒及哺乳婦甲狀腺腫及甲狀腺功能低下。<20221212>BETADINE® Throat Spray may produce mucous irritation of the mouth as well as hypersensitivity-reaction. In instances of local irritation on sensitivity discontinue use.
Weakness, confusion, oliguria or anuria, edema <20221013>Adverse Reactions
1.Dermatologic: Localized erythema, severe dermatological reaction (localized; rare)
2.Hypersensitivity: Local hypersensitivity reaction
3.Local: Application site pain (persistent or increases), local irritation, local swelling
4.Symptoms of thyroid problems: nervous, mood swings, poor sleep, tremors in the hands, rapid or irregular heartbeat, difficulty breathing, feeling hot or sweating excessively, weight loss or gain, and fatigue.
<20240415>
Adults, Elderly and Children over 6 years of age: Topical use.
Spray 2-3 times directly onto the painful and inflamed area. Repeat every 3-4 hours and used appropriately several times a day or as directed by your doctor or dentist.