治療便秘 便祕塞劑 Constipation, Preparation of bowel for procedure.
藥理
Laxative, Stimulant
藥動學
Onset of action: Rectal: 0.25 to 1 hour (suppository)
Half-life: BHPM: ~8 hours
Distribution: Vd: BHPM: 289 L (after multiple doses)
Metabolism: Bisacodyl is metabolized to an active metabolite (BHPM) in the colon; BHPM is then converted in the liver to a glucuronide salt (Friedrich 2011)
Absorption: Oral, rectal: Systemic, <5% (Wald 2003)
Excretion: BHPM: Urine, bile (Friedrich 2011)