Control of hyperphosphatemia in ESRD and dose not promote Aluminum absorption

It binds phosphorus in the GI tract better than other calcium salts due to its lower solubility and subsequent reduction in calcium or phosphorus absorption

Oral absorption is about 30% and depends on vitamin D and parathyroid hormone
crosses the placenta, appears in breast milk
excreted mainly in feces as unabsorbed calcium with 20% eliminated by the kidneys

Hypercalcemia,
calcium-phosphate producrt ﹥60-70 in the setting of uremia is associated with calcification in extraosseous tissues and should be avoided.

C

Infant risk cannot be ruled out./Calcium is excreted in breast milk with a significant loss seen during laction.

constipation or flatulence, hypophosphatemia, hypercalcemia, anorexia, vomiting, thirst

Adults: 2 tab with each meals; dosage may be increased to bring serum phosphate value to ﹤6 mg/dL