皮膚用止癢 Relief of inflammation and pruritic symptoms of corticosteroid-responsive dermatoses
藥理
Corticosteroid, Topical
藥動學
Absorption: May be increased with occlusion, inflammation, or vary with site of application Metabolism: Hepatic Excretion: Urine, feces
禁忌症
Hypersensitivity to desoximetasone or any component of the formulation.
懷孕分類
C Corticosteroids were found to be teratogenic following topical application in animal reproduction studies. In general, the use of topical corticosteroids during pregnancy is not considered to have significant risk; however, intrauterine growth retardation in the infant has been reported (rare). The use of large amounts or for prolonged periods of time should be avoided.
哺乳分類
Systemic corticosteroids are excreted in human milk. It is not known if sufficient quantities of desoximetasone are absorbed following topical administration to produce detectable amounts in breast milk. Hypertension in the nursing infant has been reported following corticosteroid ointment applied to the nipples; use with caution.
副作用
HPA-axis suppression
劑量和給藥方法
1. Apply a thin film to affected area twice daily.
2. Therapy should be discontinued when control is achieved; if no improvement is seen within 4 weeks, reassessment of diagnosis may be necessary.
小兒調整劑量
Dosage should be based on severity of disease and patient response; use smallest amount for shortest period of time to avoid HPA axis suppression.
腎功能調整劑量
There are no dosage adjustments provided in the manufacturer's labeling.
肝功能調整劑量
There are no dosage adjustments provided in the manufacturer's labeling.