Clobetasol propionate is a synthetic corticosteroid that has anti-inflammatory, antipruritic, and vasoconstrictive properties. Its anti-inflammatory effect is thought to be due to its ability to control biosynthesis of potent mediators of inflammation. It stimulates phospholipase A(2) inhibitory proteins and subsequently blocks the release of arachidonic acid, which is a common precursor to leukotrienes and prostaglandins.
藥動學
禁忌症
1. Hypersensitivity to clobetasol or any ingredient in the preparation
2. Primary scalp infection
Apply topically onto dry scalp once daily in a thin film to affected areas only; leave in place 15 minutes before lathering and rinsing; MAX 50 mL/week for 2 consecutive weeks