診斷用藥
1. Cardiac/hepatic function diagnostics: For determining cardiac output, hepatic function, and liver blood flow
2. Ophthalmic angiography
藥理
Diagnostic Agent
Indocyanine dye is a tricarbocyanine dye that permits recording of the indicator-dilution curves for both diagnostic and research purposes independently of fluctuations in oxygen saturation.
藥動學
Protein binding: 95% to albumin
Half-life elimination: 2.5 to 3 minutes
Excretion: Bile
禁忌症
Hypersensitivity to iodides
懷孕分類
Reproduction studies have not been done.
哺乳分類
The manufacturer recommends that caution be exercised when administering indocyanine green to nursing women.
Cardiac output determination:
IV 5 mg injected rapidly via a cardiac catheter; max total dose: 2 mg/kg; Flush dye from catheter with NS to prevent hemolysis Hepatic function studies:
IV 0.5 mg/kg; patient should be in a fasting basal state Ophthalmic angiography:
IV Up to 40 mg (depending on the imaging equipment and technique used); immediately follow with a 5 mL bolus of NS
小兒調整劑量
Cardiac output determination:
1. Infants: 1.25 mg injected rapidly via a cardiac catheter; maximum total dose: 2 mg/kg
2. Children and Adolescents: 2.5 mg injected rapidly via a cardiac catheter; maximum total dose: 2 mg/kg Hepatic function studies:
Refer to adult dosing
腎功能調整劑量
There are no dosage adjustments provided in the manufacturer's labeling.
肝功能調整劑量
There are no dosage adjustments provided in the manufacturer's labeling.