藥碼
EAS02
藥名
Dopamine/Dextrose 400 mg/250 mL
英文商品名
Easydopa 包 400 mg/250 mL/Bag
中文商品名
易多巴注射液
螢幕名
Easydopa 包 400 mg/250 mL/Bag
劑型
Inj
規格
400mg/250ml/bag
成分
藥理分類
Autonomic-β-Adrenergic Agonists
健保碼
AC49695265
適應症
| #建議持續輸注 (IV pump) 之高警訊藥品 |
治療心衰竭 Cardiogenic shock, septic shock, or shock due to MI, trauma, and open heart surgery; Congestive heart failure, decreased cardiac output
藥理
Dopamine hydrochloride, a natural catecholamine, is a neurotransmitter and a precursor to norepinephrine in noradrenergic nerves. It produces a positive inotropic and chronotropic effects on the myocardium by exerting an agonist action on beta-adrenoceptors and releasing norepinephrine from storage sites in sympathetic nerve endings, thus increasing heart rate and cardiac contractility.
藥動學
1. Distribution: widely distributed
2. Metabolism: Hepatic, Renal and Plasma; MAO and catechol-O-methyltransferase; hydroxylation
3. Excretion: Renal 80% primarily as metabolites, small portion unchanged
4. Elimination Half Life: 2 min
2. Metabolism: Hepatic, Renal and Plasma; MAO and catechol-O-methyltransferase; hydroxylation
3. Excretion: Renal 80% primarily as metabolites, small portion unchanged
4. Elimination Half Life: 2 min
禁忌症
Pheochromocytoma, tachyarrhythmias or ventricular fibrillation.
懷孕分類
C (FDA)
哺乳分類
No information is available on the use of dopamine during breastfeeding.
副作用
Common:
Chest pain, Hypertension, Palpitations, Tachyarrhythmia, Injection site reaction, Piloerection, Nausea, Vomiting, Headache, Mydriasis, Anxiety, Oliguria, Dyspnea
Serious:
Cardiovascular: Ectopic beats, Gangrenous disorder, Ventricular arrhythmia, Wide QRS complex
Chest pain, Hypertension, Palpitations, Tachyarrhythmia, Injection site reaction, Piloerection, Nausea, Vomiting, Headache, Mydriasis, Anxiety, Oliguria, Dyspnea
Serious:
Cardiovascular: Ectopic beats, Gangrenous disorder, Ventricular arrhythmia, Wide QRS complex
劑量和給藥方法
Bradyarrhythmia, acute symptomatic:
2 to 10 mcg/kg/min and titrate to response
Cardiac arrest (hypotension, cardiogenic shock, congestive heart failure, decreased cardiac output, septic shock):
Initial 2 to 5 mcg/kg/min; increase in 5 to 10 mcg/kg/min increments; MAX 50 mcg/kg/min
2 to 10 mcg/kg/min and titrate to response
Cardiac arrest (hypotension, cardiogenic shock, congestive heart failure, decreased cardiac output, septic shock):
Initial 2 to 5 mcg/kg/min; increase in 5 to 10 mcg/kg/min increments; MAX 50 mcg/kg/min
小兒調整劑量
腎功能調整劑量
There are no dosage adjustments provided in the manufacturer's labeling (has not been studied).
肝功能調整劑量
There are no dosage adjustments provided in the manufacturer's labeling (has not been studied).
安定性
Light sensitive and should be stored protected from light; yellow brown discoloration of the solution is an indication of decomposition and the solution should not be used.
注射給藥指引
給藥途徑
IV pump (持續靜脈輸注)
靜脈輸注液
不須稀釋
每瓶稀釋液體積
不須稀釋
注射濃度
1.6mg/mL
給藥速率
詳見「劑量和給藥方法」。
安定性
Light sensitive and should be stored protected from light; yellow brown discoloration of the solution is an indication of decomposition and the solution should not be used.
注意事項
相容：amiodarone, bumetanide, calcium chloride, calcium gluconate, cisatracurium, dexmedetomidine, diltiazem, dobutamine, dopamine, epinephrine, esmolol, fentanyl, Isoproterenol, ketamine, labetalol, lidocaine, lorazepam, magnesium sulfate, manitol, midazolam, milrinone, morphine, nicardipine, nitroglycerin, norepinephrine, octreotide, potassium chloride, propofol, vasopressin
不相容：furosemide, insulin, lansoprazole, sodium bicarbonate
* NS：0.9%生理食鹽水； D5W：5%葡萄糖水； LR：乳酸林格氏液； 1/2NS：0.45%生理食鹽水； SWFI：注射用水
不相容：furosemide, insulin, lansoprazole, sodium bicarbonate
* NS：0.9%生理食鹽水； D5W：5%葡萄糖水； LR：乳酸林格氏液； 1/2NS：0.45%生理食鹽水； SWFI：注射用水
藥袋資訊
臨床用途
低血壓、休克、心跳徐緩
主要副作用
胸痛、心悸、注射部位疼痛、頭痛、寡尿、呼吸急促
泡製方法
儲存方式
請置於 15-30℃ 乾燥處儲存
注意事項
其他說明
急首 f4 | 小庫 A4 | 藥庫 注C23 | <急救車>
藥品外觀
顏色
形狀
剝痕
標記1
標記2
其他
健保藥價
101
自費價
134.33
仿單
資料庫
健保給付規定