【藥品訊息】 Efucon 益膚康凝膠 中文仿單

皮膚用抗感染 Treatment of inflammatory lesions and erythema of rosacea, bacterial vaginosis, trichomoniasis

After diffusing into the organism, interacts with DNA to cause a loss of helical DNA structure and strand breakage resulting in inhibition of protein synthesis and cell death in susceptible organisms.

Hypersensitivity to metronidazole, parabens, or other ingredients of the formulation or other nitroimidazole derivatives; use of disulfiram within the past 2 weeks; use of alcohol or propylene glycol during therapy or within 24 hours or 3 days of therapy discontinuation.

B(UTD)

Metronidazole is excreted in breast milk following oral administration and can be detected in concentrations similar to the maternal serum.

Cardiovascular: Hypertension
Central nervous system: Headache
Dermatologic: Burning sensation of skin, erythema, skin irritation, xeroderma, acne vulgaris, contact dermatitis, pruritus, skin rash
Gastrointestinal: Metallic taste, nausea, unusual taste, xerostomia
Local: Hypersensitivity reaction
Neuromuscular & skeletal: Numbness of extremities, peripheral neuropathy, tingling of extremities
Ophthalmic: Eye irritation
Respiratory: Flu-like symptoms

Bacterial vaginosis:
(Intravaginal) One applicatorful (~37.5 mg metronidazole) intravaginally once or twice daily for 5 days
Rosacea:
(Topical) 0.75%: Apply and rub a thin film twice daily, morning and evening, to entire affected areas after washing
Trichomoniasis:
(Intravaginal) 10% Insert one applicatorful (equal to metronidazole 500 mg) intravaginally once or twice daily for 10 or 20 consecutive days (even during menses)