局部麻醉 Topical local anesthetic (normal intact skin)

Lidocaine blocks both initiation and conduction of nerve impulses by decreasing ionic flux through the neuronal membrane, which results in local anesthesia after topical application. Prilocaine hydrochloride exhibits local anesthetic action by stabilizing the neuronal membrane through inhibition of the ionic fluxes necessary for the initiation and conduction of impulses.

Hypersensitivity to amide-type anesthetics

B

Infant risk can not be ruled out.

Application site erythema, application site pain, body pale

Major dermal procedure: apply 2 g of CREAM per 10 cm² of skin; allow to remain in contact with skin for at least 2 hr.
Minor dermal procedure: apply 2.5 g of CREAM over 20-25 cm² of skin surface.

Age 0-3 months or weight＜5 kg:
MAX dose 1g; MAX application area, 10 cm²; MAX application time 1 hr.
Age 3-12 months, weight＞5 kg:
MAX dose 2 g; MAX application area, 20 cm²; MAX application time, 4 hr.
Age 1-6 yr, weight>10 kg:
MAX dose 10 g; MAX application area, 100 cm²; MAX application time, 4 hr.
Age 7-12 yr, weight>20 kg:
MAX dose 20 g; MAX application area, 200 cm²; MAX application time, 4 hr.