Absorption: through the cornea. No systemic accumulation detected. Metabolism: primarily hepatic through oxidation, N-dealkylation, glucuronidation, sulfate, and/or taurine conjugation. Time to peak: 10 to 15 minutes after ocular administration.
禁忌症
懷孕分類
If ophthalmic agents are needed during pregnancy, the minimum effective dose should be used in combination with punctal occlusion to decrease potential exposure to the fetus.