Low urinary tract symptoms associated with benign prostatic hyperplasia.良性前列腺肥大症所伴隨的下泌尿道症狀
#仿單變更2020

tamsulosin binds selectively and competitively to the postsynaptic a₁-adrenoceptor, in particular to subtypes a_1A and a_1D. It relieves obstruction by relaxing smooth muscle in prostate and urethra thereby improving voiding symptoms. It also improves the storage symptoms in which bladder instability plays an important role.

approximately 57 % is estimated to be absorbed from the intestine; Time to peak: at a median time of 6 hours; plasma Protein binding: 99%; Metabolism: in liver via CYP3A4 and 2D6, metabolites undergo extensive conjugation to glucuronide or sulfate; Elimination half-life: 10 - 15 hr.

Hypersensitivity to tamsulosin hydrochloride or to any of the excipients; A history of rthostatic hypotension; Severe hepatic insufficiency.

Not applicable, as Harnalidge^â OCAS^â 0.4 mg is intended for male patients only!

Not applicable, as Harnalidge^â OCAS^â 0.4 mg is intended for male patients only!

Dizziness, headache, abnormal ejaculation, rhinitis, back pain, rash, skin photosensitivity<20201222>.

 Orally , one tablet 0.4 mg daily.