【藥品性質提示】 根據 2019 AGS Beers Criteria，本藥品為【潛在不適當用藥 (PIM)】，不建議用於有骨折風險之老年人(除非用於癲癇、調節情緒)。

治療癲癇 In combination with other anticonvulsant agents in the management of partial seizures

The major role of lamotrigine appears to be in the treatment of simple and complex partial seizures and secondarily generalized tonic-clonic seizures resistant to multiple-drug therapy.

It is contraindicated in patients with known hypersensitivity to the drug or any ingredient in the formulation.

C

Lamotrigine is distributed into milk. A decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the woman.

1. Common: dizziness, headache, ataxia, nausea, vomiting, rhinitis, pharyngitis, diplopia, and blurred vision.
2. Serious: Stevens Johnson syndrome or rare deaths due to toxic epidermal necrolysis have been reported.

Monotherapy: 200-500 mg/day in two divided doses, up to 700 mg/day have been used in some cases.
Combination use with valproic acid: 100-150 mg/day

The drug is not approved for use in patients below 16 of age, due to higher incidence of severe life-threatening skin rash than in adult.