治療成人(18 歲以上)感受性細菌引起的感染症：急性鼻竇炎、慢性?氣管炎的急性惡化、社區性肺炎、皮膚和軟組織的感染、複雜腹腔內感染(包括多種細菌感染症)。

Antibiotic, Fluoroquinolone; Antibiotic, Respiratory Fluoroquinolone

Absorption: well absorbed; not affected by high-fat meal or yogurt.
Distribution: 1.7 to 2.7 L/kg (tissue concentrations often exceed plasma concentrations in respiratory tissues, alveolar macrophages, abdominal tissues/fluids, uterine tissue, and sinus tissues).
Protein binding: ~30% to 50%.
Metabolism: hepatic via glucuronide and sulfate conjugation.
Bioavailability: ~90%.
Half-life elimination: ~11.5 to 15.6 hours.
Excretion: urine, feces.

Hypersensitivity to moxifloxacin, other quinolone antibiotics, or any component of the formulation

C

<10%: headache (4%), dizziness (3%), insomnia (2%), decreased serum glucose (≥2%), hyperchloremia (≥2%), increased serum albumin (≥2%), nausea (7%), diarrhea (6%), decreased amylase (≥2%), constipation (2%), vomiting (2%), decreased basophils (≥2%), decreased red blood cells (≥2%), eosinopenia (≥2%), increased MCH (≥2%), increased neutrophils (≥2%), leukocytosis (≥2%), prolonged prothrombin time (≥2%) , decreased serum bilirubin (≥2%), increased serum bilirubin (≥2%), increased serum globulins (≥2%), increased ionized serum calcium (≥2%), hypoxia (≥2%).

Acute sinusitis, acute exacerbations of chronic bronchitis, community-acquired pneumonia, infections of the skin and soft tissues, complicated intra-abdominal infection:
the recommended dose is one film-coated tablet 400 mg once a day.

No dosage adjustment necessary.

No dosage adjustment necessary.