seasonal and perennial allergic rhinitis and nasal polyps

Mometasone furoate is a corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Corticosteroids have a wide range of effects on various cell types (including mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (including histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation

Mometasone furoate has negligible(≦0.1%) systemic bioavailability and is generally undetectable in plasma

Hypersensitivity to mometasone furoate or any ingredients of Nasonex

C

Avoided/Infant risk cannot be ruled out

headache, epistaxis, pharyngitis, nasal burning, nasal irritation,and nasal ulceration

Allergic rhinitis:
(Adults and children≧12 yrs) 2 spray/nostril once daily (200 mcg/day)
Nasal polyps:
(≧18yrs) 2 spray/nostril twice daily (400 mcg/day)

Children (2-11 yrs): 1 spray/nostril once daily (100 mcg/day)