Betahistine is an analog of histamine with weak agonist properties at histamine H1 receptors and more potent anatgonistic effects at histamine H3 receptors.
藥動學
Betahistine is rapidly absorbed following oral administration. Betahistine is converted to 2-pyridylacetic acid, presumably in the liver. The majority of a dose of betahistine is excreted in the urine as metabolites within 3 days of oral administration.
禁忌症
Phaeochromocytoma, Asthma,Gastric or duodenal ulcer.
懷孕分類
Australian Drug Evaluation Committee's (ADEC) Category: B2.