【藥品性質提示】 ★LASA藥品：NES01 NESP (Darbepoetin) 針 紅 20mcg (形似) 點擊看LASA藥品外觀比較圖

嗜中性白血球補充 (化療致骨髓抑制、骨髓移殖、慢性白血球低下症)
Chemotherapy-induced myelosuppression in nonmyeloid malignancies: To decrease the incidence of infection (neutropenic fever) in patients with nonmyeloid malignancies receiving myelosuppressive chemotherapy associated with a significant incidence of severe neutropenia with fever
Bone marrow transplantation: To reduce the duration of neutropenia and neutropenia-related events (eg, neutropenic fever) in patients with nonmyeloid malignancies receiving myeloablative chemotherapy followed by marrow transplantation
Severe chronic neutropenia: Long-term administration to reduce the incidence and duration of neutropenic complications (eg, fever, infections, oropharyngeal ulcers) in symptomatic patients with congenital, cyclic, or idiopathic neutropenia

Colony Stimulating Factor
Filgrastim is a human granulocyte colony-stimulating factor (G-CSF) which acts on hematopoietic cells by binding to specific cell surface receptors and regulating neutrophil production, progenitor proliferation, and differentiation. It also affects some end-cell functional activation including phagocytic activity, cellular metabolism, and antibody-dependent killing.

Distribution: Vd: 150 mL/kg
Elimination Half Life: approximately 3.5 hr

1. Previous hypersensitivity to myeloid growth factors.
2. Administered within 24 hours, before or after, receiving cytotoxic chemotherapy.

C

Avoid; because a risk of infant exposure to GCSF exists, caution should be exercised when administering this agent to nursing mothers

Bone pain (Administration of acetaminophen prior to therapy may prevent or reduce the occurrence of bone pain), nausea, vomiting, Influenza-like illness

Should be stored at 2-8℃. Avoid shaking the solution. Discard any filgrastim solution that has been at room temperature for＞24 hr.