Allergic rhinitis; Congestion of nasal sinus; Common cold
藥理
Pseudoephedrine acts as a decongestant by stimulating alpha-adrenergic receptors of vascular smooth muscle, thus constricting dilated arterioles within the nasal mucosa and reducing blood flow to the engorged area/Triprolidine is a member of the propylamine (alkylamine) chemical class of H-1 antagonist antihistamines.
藥動學
Metabolism Liver, extensive
Elimination Half-life: 2.1 to 16 hours
禁忌症
hypersensitivity to pseudoephedrine or sympathomimetics or triprolidine
neonates
angle-closure glaucoma
hypertension, severe
MAOI therapy
coronary artery disease, severe