Elevated intraocular pressure
Glaucoma
Miosis
Prevention of postoperative elevated IOP.

Pilocarpine is a parasympathomimetic that directly stimulates cholinergic receptors. Through contraction of the iris sphincter muscle, increased tension on the scleral spur and opening of the trabecular meshwork spaces occurs to facilitate the outflow of aqueous humor. Intraocular pressure is reduced as outflow resistance is reduced.

Excretion:
Renal: unchanged and degradation products; extent not described.
Elimination Half Life:
healthy volunteers: 0.76 to 1.35 hours
hepatic impairment, mild to moderate: 2.1 hours .

conditions in which miosis is undesirable (eg, acute iritis , narrow-angle glaucoma)
hypersensitivity to pilocarpine hydrochloride or any component of the product
pupillary block glaucoma (ophthalmic solution)
uncontrolled asthma (oral formulation) .

C (FDA)

Compatible with breastfeeding.(WHO)
Infant risk cannot be ruled out.(MDX).

Common:
Dermatologic: Sweating (29% to 68% )
Neurologic: Headache (11% to 13% )
Serious:
Cardiovascular: Pulmonary edema
Ophthalmic: Retinal detachment.

Instill 1~2 drop into the affected eye(s).(UTD)