Active immunization against invasive disease (including sepsis, meningitis, bacteraemic pneumonia, bacteraemia, and empyema) caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F in infants and young children

Prevenar 13 contains the 7 pneumococcal capsular polysaccharides that are in Prevenar(4, 6B, 9V, 14, 18C, 19F, 23F) plus 6 additional polysaccharides (1, 3, 5, 6A, 7F, 19A) all conjugated to CRM197 carrier protein and induce a T cell-dependent immune response.
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NA

Hypersensitivity to the active substances or to any component of the product, or to diphtheria toxoid.

C

It is not known if antigens contained in Prevenar are distributed into milk. The vaccines should be used with caution in nursing women.

Injection site reactions (e.g. erythema, induration/swelling, pain/tenderness); fever ＞38 °C, irritability, drowsiness, restless sleep; decreased appetite, vomiting, diarrhea.

The vaccine should be given by intra-muscular injection.Infants aged 2 - 6 months: three single doses of 0.5 ml at interval of 1 month, starting at 2 months of age and with a fourth dose given in the second year of life.Previously unvaccinated older infants and children:Infants aged 7 - 11 months:two doses, each of 0.5 ml, with an interval of at least 1 month between doses. A third dose is recommended in the second year of life.Children aged 12 - 23 months: two doses, each of 0.5 ml, with an interval of at least 2 months between doses.Children aged 24 months – 5years: one single dose.

Store at 2 – 8 °C and Do not freeze.