Habitual abortion, premature labor, uterine bleeding, dysmenorrhoea and female hypogonadism.

Progesterone is a naturally occurring progestin secreted by the corpus luteum and is the prototype of the progestins.Progesterone is a progestinic hormone secreted mainly from the corpus luteum of the ovary during the latter half of the menstrual cycle.

Severe hepatic and renal disease, missed and incomplete abortion.

D

Progestins are reportedly distributed into milk. The manufacturers warn that the possible effects of progestins in milk on nursing infants have not been determined.

Skin rash, edema, weight gain, GI disorders and headache.

Endometrial hyperplasia; Prophylaxis:Oral micronized progesterone should be given as a single daily dose in the evening, 200 mg for 12 days sequentially per 28-day cycle, to postmenopausal women with a uterus who are receiving daily conjugated estrogen tablets. Secondary physiologic amenorrhea:Oral progesterone may be given as a single daily dose of 400 mg in the evening for 10 days.