Finasteride is used orally to stimulate regrowth of hair in men with mild to moderate androgenetic alopecia (male pattern alopecia, hereditary alopecia, common male baldness). Benign prostatic hyperplasia. Finasteride causes a decrease in serum prostate-specific antigen, a marker commonly used for the detection of prostatic carcinoma. Patients should be screened for prostatic carcinoma by other methods (digital rectal exam) prior to and during finasteride therapy.
藥理
Finasteride is a 5-alpha reductase inhibitor; it inhibits the conversion of testosterone to dihydrotestosterone. But several weeks of therapy are often required before any benefit noted by the patient. Combination therapy with finasteride and an alpha-blocker may provide optimal medical management.
Contraindication: Hypersensitivity to finasteride and pregnancy; It is not indicated for use in women or children.
藥動學
禁忌症
Hypersensitivity to finasteride and pregnancy; It is not indicated for use in women or children.
懷孕分類
X
哺乳分類
副作用
Rash, breast tenderness, erectile dysfunction, reduced libido
劑量和給藥方法
For treatment of androgenetic alopecia in men, the usual dosage of finasteride is 1 mg once daily.1 Daily administration of the drug for 3 months or longer generally is necessary before benefit is observed. No dosage adjustment is necessary in patients with chronic renal insufficiency.
小兒調整劑量
腎功能調整劑量
No dosage adjustment is necessary in patients with chronic renal insufficiency