藥碼
PRO18
藥名
Isoproterenol 0.2 mg/1 mL/amp
英文商品名
Isoproterenol 針 0.2 mg/1 mL/Amp
中文商品名
樂普他諾注射劑
螢幕名
Isoproterenol 針 0.2 mg/1 mL/Amp
劑型
Inj
規格
Inj 0.2 mg/ml/Amp
成分
藥理分類
Autonomic-β-Adrenergic Agonists
健保碼
AC58806209
ATC碼
適應症
| #建議持續輸注 (IV pump) 之高警訊藥品 |
治療心律不整 Bronchial spasm; Cardiac Arrhythmias and Cardiac Arrest; Shock
藥理
Beta1/Beta2 Agonist
Isoproterenol hydrochloride is a synthetic sympathomimetic agent that acts directly on both β1- and β2-adrenergic receptors (nonselective β-agonist).
Isoproterenol hydrochloride is a synthetic sympathomimetic agent that acts directly on both β1- and β2-adrenergic receptors (nonselective β-agonist).
藥動學
1. Onset of action: Immediate
2. Duration: 10-15 minutes
3. Metabolism: Via conjugation in many tissues including hepatic and pulmonary
4. Half-life elimination: 2.5-5 minutes
5. Excretion: Urine (primarily as sulfate conjugates)
2. Duration: 10-15 minutes
3. Metabolism: Via conjugation in many tissues including hepatic and pulmonary
4. Half-life elimination: 2.5-5 minutes
5. Excretion: Urine (primarily as sulfate conjugates)
禁忌症
Angina, preexisting ventricular arrhythmias, tachyarrhythmias; cardiac glycoside intoxication
懷孕分類
C
哺乳分類
The manufacturer recommends that caution be exercised when administering isoproterenol to breastfeeding women.
副作用
Tachycardia, palpitation, hypotension, headache, precordial pain, flushing, nervousness, tremor, weakness.
劑量和給藥方法
(Continuous IV infusion) Usual range 2 to 10 mcg/minute; titrate to patient response
小兒調整劑量
腎功能調整劑量
肝功能調整劑量
安定性
注射給藥指引
給藥途徑
IV pump (持續靜脈輸注)
靜脈輸注液
D5W (MDX)
每瓶稀釋液體積
0.2~1.0mg Isoproterenol 溶解於 200~500mL 之等張溶液內；緊急時以 0.2mg 溶解於 20mL 等張溶液內注射 (仿單)
注射濃度
心臟阻滯、Adams-Stokes attacks、心臟驟停：最終濃度 0.004mg/mL；休克、器官低灌注：最終濃度 0.002mg/mL (MDX)
給藥速率
詳見「劑量和給藥方法」
安定性
注意事項
相容：amiodarone, bumetanide, calcium chloride, calcium gluconate, dexmedetomidine, diltiazem, dobutamine, dopamine, epinephrine, esmolol, fentanyl, heparin, labetalol, lidocaine, lorazepam, magnesium sulfate, manitol, midazolam, milrinone, morphine, nicardipine, nitroglycerin, norepinephrine, octreotide, potassium chloride, propofol, vasopressin
不相容：aminophylline, insulin, pantoloc, sodium bicarbonate!!!
完整資訊請見重症常用藥品靜脈相容性表
不相容：aminophylline, insulin, pantoloc, sodium bicarbonate!!!
完整資訊請見重症常用藥品靜脈相容性表
藥袋資訊
臨床用途
心跳徐緩、心臟功能不全
主要副作用
心跳快速、心悸、頭痛、不安、顫抖等
泡製方法
儲存方式
請置於 15-30℃ 乾燥處儲存
注意事項
其他說明
急首 e2 | 藥庫 注G12 | 自批號304615起品名變更(舊：Proternol-L/普樂他諾，新：Isoproterenol/樂普他諾)。<2023/2/7>
藥品外觀
顏色
形狀
剝痕
標記1
標記2
其他
健保藥價
190
自費價
252.7
仿單
資料庫
健保給付規定