Fluticasone: Corticosteroid, Inhalant
A corticosteroid with anti-inflammatory activity, immunosuppressive properties, and antiproliferative actions. Vilanterol: Beta2-Adrenergic Agonist, Long-Acting
A long-acting beta2-agonist, relaxes bronchial smooth muscle by selective action on beta2-receptors with little effect on heart rate.
藥動學
禁忌症
1. Hypersensitivity to fluticasone, vilanterol, or any component of the formulation
2. Severe hypersensitivity to milk proteins
3. Primary treatment of status asthmaticus or other acute episodes of COPD or asthma where intensive measures are required
懷孕分類
Adverse events have not been observed in animal reproduction studies
哺乳分類
It is not known if sufficient quantities of fluticasone or vilanterol are absorbed following inhalation to produce detectable amounts in breast milk.
Asthma: One inhalation once daily. (MAX 1 inhalation once daily)
小兒調整劑量
腎功能調整劑量
No dosage adjustment necessary.
肝功能調整劑量
1. Mild impairment: There are no dosage adjustments provided in the manufacturer's labeling.
2. Moderate to severe impairment: There are no dosage adjustments provided in the manufacturer's labeling; however, systemic fluticasone exposure may be increased up to threefold in patients with hepatic impairment; use with caution and monitor closely.