Prevention of Rh HDN and the prevention of isoimmunization in Rho(D)-negative individuals who have been transfused with Rho(D)-positive blood or blood components containing red blood cells.

HyperRHO S/D is an immune globulin with a high level of preformed antibodies against rhesus (Rh)-positive blood cells.
The injection of an RHo(D) immune globulin provides a passive immunity for rapid immune protection and an acute response in high-risk situations.
HyperRHO S/D destroys any Rh-positive blood cells that may have entered the mother's bloodstream and prevents the mother's immune system from producing Rh-positive antibodies, thus protecting the baby from developing hemolytic disease.

Injection site pain、increase in body temperature

Postpartum prophylaxis—preferably within 72 hours of delivery
1.If volume of red blood cells that has entered the circulation is 15 mL : 1500 IU or 300 mcg IM.
2.If large (>30 mL whole blood or 15 mL red blood cells) fetomaternal hemorrhage is suspected : Fetal red blood cell count should be performed to determine dosage.
Antenatal prophylaxis
1.At approximately 28 weeks' gestation. Then, postpartum, preferably within 72 hours of delivery, if infant is Rh positive : 1500 IU or 300 mcg IM.