Riluzole is a glutamate antagonist. Riluzole has been reported to confer a survival benefit to the subgroup of patients with bulbar-onset amyotrophic lateral sclerosis.
藥理
The efficacy of riluzole in amyotrophic lateral sclerosis remains unclear.
藥動學
禁忌症
Hypersensitivity to riluzole
懷孕分類
C
哺乳分類
No human data available to assess risk of infant harm or effects on milk production; caution advised while breastfeeding.
副作用
asthenia, elevation of serum transaminases, worsening of spasticity, gastrointestinal symptoms, and blood pressure elevations.