孩童及青少年：
1. 腦下垂體生長激素分泌不足所導致之生長遲滯。
2. 其他Gonadol Dysgenesis (Turner's syndrome)所導致之生長遲滯。
3. 青春期前因慢性腎臟衰竭導致之生長遲滯。
4. 低出生體重兒(Small for Gestational Age; SGA)逾四歲者之生長障礙。
成人：生長激素嚴重分泌不足之補充療法。

Growth Hormone

Metabolism: hepatic and renal.
Bioavailability: 70% to 90%.
Half-life elimination: ~2 hours.
Excretion: urine.

Hypersensitivity to somatropin or any component of the formulation; growth promotion in pediatric patients with closed epiphyses; acute critical illness due to increased complications/mortality following open heart or abdominal surgery, multiple accidental trauma, or acute respiratory failure; active malignancy; active proliferative or severe nonproliferative diabetic retinopathy.

>10%: peripheral edema (≤69%), facial edema (≤50%), edema (adults: ≤41%; children: ≤3%), lower extremity edema (adults: ≤15%), pain (≤19%), hypoesthesia (≤15%), headache (adults: ≤18%; children: ≤7%), paresthesia (≤13%), hypothyroidism (children: ≤16%; adults: ≤5%), elevated glycosylated hemoglobin (children: ≤14%), eosinophilia (children: ≤12%), nausea (≤13%), flatulence (≤25%), abdominal pain (≤25%), vomiting (≤19%), Antibody development (children: ≤24%), infection (adults: ≤13%), pain at injection site (≤31%), injection site reaction (≤19%), arthralgia (≤44%), arthropathy (adults: ≤27%; children: 11%), myalgia (≤30%), scoliosis (children: ≤19%), limb pain (4% to 19%), swelling of extremities (18%), ostealgia (adults: ≤11%), otitis media (children: ≤16%), upper respiratory tract infection (≤16%).

It is recommended to inject subcutaneously before going to bed.
Children and teenagers:
(1) Growth hormone deficiency (GHD): 0.18 mg/kg weekly divided into equal doses 3, 6, or 7 days/week.
(2) Turner syndrome, Growth failure secondary to chronic kidney disease (CKD) : 1.4 mg/square meter of body surface area or 0.045~0.050 mg/kg of body weight.
(3) Growth retardation of low birth weight infants: 0.035 mg/kg body weight per day subcutaneous injection.
Adults:
Growth hormone deficiency: ≤0.005 mg/kg/day; dose may be increased up to 0.01 mg/kg/day after 4 weeks; Maximum:1 mg/day.

It can be maintained at 2-8 degrees for 28 days; It can be at 25 degrees for 7 consecutive days.