Gas retention : Relief of pressure, bloating, fullness, and discomfort of gastrointestinal gas.
藥理
Antiflatulent: Decreases the surface tension of gas bubbles thereby disperses and prevents gas pockets in the GI system.
藥動學
Excretion: Feces
禁忌症
1.hypersensitivity to simethicone products 2.known or suspected intestinal perforation and obstruction
懷孕分類
Dimethicone is not absorbed systemically following topical administration. Use during pregnancy would not be expected to result in significant exposure to the fetus.
哺乳分類
Due to lack of systemic absorption, simethicone is not expected to be present in breast milk
副作用
Gastrointestinal: Diarrhea (Mild), Nausea, Regurgitation of gastric content, Vomiting
劑量和給藥方法
1.Gas retention: Usual dose: 40 to 125 mg 4 times daily as needed after meals and at bedtime.
小兒調整劑量
1.Gas pain / gastrointestinal discomfort: 20 mg 4 times daily (Infants and Children <2 years weighing <10.9 kg),40 mg 4 times daily(Children <2 years weighing ≥10.9 kg and Children ≥2 to <12 years),40 to 125 mg 4 times daily (Children ≥12 years and Adolescents)
腎功能調整劑量
There is no dosage adjustment provided in the manufacturer’s labeling.
肝功能調整劑量
There is no dosage adjustment provided in the manufacturer’s labeling.