Metabolism: fatty acids, phospholipids, and glycerol are metabolized by cells to adenosine triphosphate (ATP), carbon dioxide, and water. Excretion: biliary (phospholipids).
禁忌症
Hypersensitivity to fish, egg, soybean, or any other component of the formulation; severe disorders of lipid metabolism characterized by hypertriglyceridemia (serum triglyceride concentrations >1,000 mg/dL); severe hepatic insufficiency; severe blood coagulation disorders; severe renal insufficiency without access to hemofiltration or dialysis; acute shock; acute pulmonary edema; hyperhydration; decompensated cardiac insufficiency.
Energy/calories: IV: 1 to 2 g/kg/day; daily dose may be infused over 12 to 24 hours; maximum daily dose: 2.5 g/kg/day; infusion rate: 0.125-0.15 g/kg/hr.
小兒調整劑量
Parenteral nutrition (infusion rate: <0.15 g/kg/hr):
<2 years: IV: Initial: 0.5 to 1 g/kg/day; increase by 0.5 to 1 g/kg/day to a maximum daily dose of 3 g/kg/day.
2 to <12 years: IV: Initial: 1 to 2 g/kg/day; increase by 0.5 to 1 g/kg/day to a maximum daily dose of 3 g/kg/day.
Children ≥12 years and Adolescents: IV: Initial: 1 to 2 g/kg/day; maximum daily dose: 2.5 g/kg/day.