【藥品性質提示】
★LASA藥品:GLU07 D50W 大包 500 mL (形似)
點擊看LASA藥品外觀比較圖
★必確認適應症:低血鈉、顱內壓過高、哮吼
#高警訊藥品
Hypotonic sodium chloride solution (0.45%): fluid replacement when fluid losses exceed electrolyte depletion. Isotonic solution (0.9%): Restores water/sodium losses. Hypertonic solution (3%): For severe hyponatremia and hypochloremia
藥理
Sodium chloride is a source of water and electrolyte . Sodium is the principle cation of extracellular fluid and chloride is the principle anion of extracellular fluid. Sodium content normally determines the volume of extracellular fluid, and important in the regulation of osmolarity, acid-base balance, and the membrane potential of cells
藥動學
禁忌症
Congestive heart failure, severe renal impairment, edema with sodium retention.
懷孕分類
C
哺乳分類
副作用
Common: Phlebitis, Injection site extravasation, Injection site reaction, Hypervolemia
劑量和給藥方法
Hyponatremia: dose should be guided by serum sodium levels, clinical condition, patient age and weight. ≧3% solutions: Administration through a central line is recommended due to high osmolarity and tonicity. To calculate sodium deficit use the following formula: (140 mEq/L - patient's serum Na) x (total body water in liters) = mEq Na. Using hypertonic (3% or 5%) solutions for replacement, administer half of dose over 8 hours, not to exceed a maximum of 100 milliliter/hour. Continue treatment until serum sodium is 130 mEq/L or neurologic symptoms improve. Remainder of deficit can be replaced over several days