治療貧血鐵劑 Iron deficiency due to chronic blood loss, pregnancy, premature babies, severe pernicious anemia

Patients receiving repeated blood transfusions or with anemias not produced by iron deficiency; with iron-storage or iron-absorption diseases, haemoglobinopathies, or exisitng GI disease.

D

No data available, iron excreted in the milk is about 0.25mg/day during normal lactation period.

Therapeutic dose may cause mild GI discomfort, diarrhea, vomiting; side effect is reduced by taking it with or immediately after food; constipation (large dose > 180mg iron/day), irritant and corrosive effects on GI mucosa, and necrosis and perforation may occur.

1. Usual therapeutic dosage : Adults: PO 50-100mg of elemental iron TID; children: elemental iron 4-6mg/kg/day in 3 divided doses.
2. Prevent iron deficiency: pregnant women: 30mg of iron, not breast-fed infants: 1mg/kg/day, max 10mg/day; low-birth-weight infants: 2mg/kg/day for 2 months, max 15mg/day; more than 10-year old children: male : 2mg/day, female 5mg/day.
Administration rate: Dilute the calculated dose in 200-1000ml of NS infusion over 1-6 hours
3. IV dose calculation: mg FE requirement = Body weight (kg) x (15-(Hb/100 ml) x 2.4 +500; maximum daily dose of Fe in IV form: children < 5 kg, 1.25 ml (1/4 amp); children 5-10 kg, 5 ml (1/2 amp); adult, 10 ml (1 amp).