Analgesic, Urinary
Oral urinary tract analgesic. It is used for the symptomatic relief of pain, burning, urgency, frequency, and other discomforts resulting from irritation of the lower urinary tract mucosa, including symptomatic relief of urinary tract infection (UTI) symptoms.
藥理
An azo dye which exerts local anesthetic or analgesic action on urinary tract mucosa through an unknown mechanism.
藥動學
Metabolism:Rapidly reduced. Excretion:Renal: Up to 90% is excreted.
禁忌症
Hypersensitivity to phenazopyridine or any component of the formulation; renal insufficiency.
懷孕分類
B
Phenazopyridine crosses the placenta and can be detected in amniotic fluid .
哺乳分類
Phenazopyridine and its metabolites (i.e., aniline) may have the potential to produce methemoglobinemia.
副作用
Adverse reactions reported with use of phenazopyridine include headache, rash (unspecified), pruritus, anaphylactoid reactions, and gastrointestinal disturbances.
劑量和給藥方法
1.Dysuria, symptomatic relief: 200 mg 3 times daily.
小兒調整劑量
腎功能調整劑量
CrCl <50 mL/minute: Avoid use. Cases of acute kidney injury, hemolytic anemia, and methemoglobinemia have been reported.