【藥品性質提示】 ★LASA藥品：SYN06 Syntrend 錠劑 藍字 25mg (形似) 點擊看LASA藥品外觀比較圖

mild-to-moderate hypertension, angina, and congestive heart failure

Antihypertensive; Beta-Blocker With Alpha-Blocking Activity

The drug is extensively metabolized in the liver and primarily excreted via the feces; the elimination half-life of carvedilol is 6 to 8 hours.

Bronchial asthma or chronic obstructive pulmonary disease, cardiogenic shock, hypersensitivity, overt cardiac failure, second and third degree AV block, severe sinus bradycardia, sick sinus syndrome, and severe liver failure

C.
Carvedilol may be considered for use in pregnant patients with heart failure. If maternal use of a beta-blocker is needed, fetal growth should be monitored during pregnancy and the newborn should be monitored for 48 hours after delivery for bradycardia, hypoglycemia, and respiratory depression.

Carvedilol is highly lipophilic with a large volume of distribution, and therefore may accumulate in human breast milk.

dizziness; other adverse effects include fatigue, hypotension, bradycardia, headache, bronchospasm, skin rash

Hypertension: 6.25 mg PO BID, may be increase to 12.5-25 mg BID
CHF: 3.125 mg PO BID, may be doubled every 2 weeks up to a maximum dose of 25-50 mg BID

No dosage adjustment necessary; Unlikely to be dialyzed

Mild to moderate impairment: There are no dosage adjustments provided in the manufacturer’s labeling.
Severe impairment: Use is contraindicated.