【藥品訊息】 Trimbow 吸入劑 100/6/12.5mcg 衛教單張

慢性阻塞性肺病 COPD
用於FEV1少於預測值之50%及惡化病史之COPD成年病人；在已使用吸入型皮質類固醇與長效beta 2致效劑合併療法仍未得到充分治療時，作為維持治療使用

1. Beclometasone dipropionate: Corticosteroid, Inhalant (Oral)
2. Formoterol: Beta2 Agonist, Long-Acting
3. Glycopyrronium: Anticholinergic Agent, Long-Acting

搭配 AeroChamber Plus 輔助器使用 Trimbow，曾提高進入肺內的 beclometasone 17-monopropionate(15%)、formoterol(58%) 和 glycopyrronium(60%) 藥量(Cmax)

對活性物質或對Ethanol anhydrous, Hydrochloric acid, Norflurane（推進劑）等賦形劑過敏

Limited data available; avoid using during pregnancy

It is not known if it is present in breast milk.

Oral candidiasis (caused by), Muscle cramps (caused by β2-agonist)

Adult: 2 puff BID

Not available in children

Mild to moderate renal impairment: No dosage adjustment necessary
Severe impairment OR ESRD: Consider risk and benefit before use.

1. Limited data available in severe impairment patients; Use with caution
2. Formoterol 主要是經由肝臟代謝排除，因此可預期重度肝功能不全病人的 formoterol 暴露量會增加