慢性阻塞性肺病 COPD
Maintenance treatment in patients with chronic obstructive pulmonary disease
藥理
Indacaterol: Beta2-Adrenergic Agonist, Long-Acting
Relaxes bronchial smooth muscle by selective action on beta2-receptors with little effect on heart rate; acts locally in the lung. Glycopyrronium: Anticholinergic Agent
In COPD, competitively and reversibly inhibits the action of acetylcholine at muscarinic receptor subtypes 1 and 3 in bronchial smooth muscle thereby causing bronchodilation.
藥動學
Onset of action: within 5 minutes after dosing.
Duration: 24 hours
禁忌症
1. Hypersensitivity to indacaterol maleate, or glycopyrronium bromide, or any component of the formulation
2. Severe hypersensitivity to milk proteins
Oral inhalation:
Contents of 1 capsule (indacaterol 110 mcg/glycopyrronium 50 mcg) inhaled once daily using Ultibro Breezhaler device. Note:
1. Dose delivered per capsule is equivalent to indacaterol 85 mcg/glycopyrronium 43 mcg
2. Not to be used for the relief of acute attacks
3. Administer once daily at the same time each day