【缺藥訊息】 公告日期：2022/11/9。 缺藥品項：Unasyn 錠劑 375mg。 缺藥原因：原料問題導致藥品短缺。 替代藥品：國內無同成份規格藥品替代。 配套措施：用罄關檔停用，改用院內同類藥品 (Curam 口溶錠 625mg) 替代。

Penicillin類抗生素 Infections caused by Sulbactam/Ampicillin sensitive organisms, including Streptococcus , Staphylococcus ,E. coli, Klebsiella, Serratia, H. influenzae, Proteus mirabilis, Citrobacter spp. and anaerobic bacterium (Bacteroides Fusobacterium, Closteridium Difficile)

Sultamicillin is a 1:1 combination of ampicillin and sulbactam in ester form. It have a broad antibacterial spectrum covering gram-positive and gram negative organisms. Its action is bactericidal.

1. Bioavailability: 80%
2. Renal Excretion: 60% to 75% as unchanged drug

Hypersensitivity to penicillins (eg, anaphylaxis)

B

Infant risk is minimal

skin rash, abdominal pain, diarrhea, nausea, vomiting

Usual dose: 375mg of sultamicillin two to three times daily