Common cold: To reduce the duration and severity of symptoms associated with the common cold. Dietary supplement: For use as a dietary supplement.
藥理
Trace Element
藥動學
Absorption: Small intestine Distribution: Stored primarily in skeletal muscle and bone Protein binding: Primarily to albumin Excretion: Feces and urine
禁忌症
There are no contraindications listed in the manufacturer's labeling.
懷孕分類
Zinc crosses the placenta and can be measured in the cord blood and placenta. Fetal concentrations are regulated by the placenta (de Moraes 2011). The RDA is increased during pregnancy.
哺乳分類
Zinc is found in breast milk; concentrations decrease over the first 6 months of lactation. Concentrations are generally not affected by dietary supplementation. The maternal RDA is increased in nursing women.
副作用
Frequency not defined; may vary with different salts. Adverse reactions reported with excess dietary zinc Central nervous system: Headache Endocrine & metabolic: Copper deficiency, decreased HDL cholesterol, decreased LDL cholesterol. Gastrointestinal: Abdominal cramps, decreased appetite, diarrhea, epigastric pain, gastrointestinal distress, nausea, vomiting Hematologic & oncologic: Immunodeficiency
劑量和給藥方法
Common cold: Note: For best results, begin therapy 24 to 48 hours prior to symptom onset: Oral: Dissolve one 13.3 mg lozenge in mouth every 2 to 4 hours as needed. Maximum: 6 lozenges daily. Dietary supplement: Oral: One capsule/tablet daily or as directed by health care provider.
小兒調整劑量
Common cold: Note: Consult product-specific labeling for manufacturer-recommended ages. For best results, begin therapy 24 to 48 hours prior to symptom onset: Cold-Eeze Lozenge: Children ?12 years and Adolescents: Oral topical: Dissolve one lozenge in mouth every 2 to 4 hours as needed. Age-dependent maximum daily dose: 12 to 17 years: 4 lozenges/day; ?18 years: 6 lozenges/day. Zinc deficiency, treatment: Limited data available: Note: Dosage expressed in terms of elemental zinc (Kliegman 2016) Acquired: Infants, Children, and Adolescents: Oral: 0.5 to 1 mg/kg/day Acrodermatitis enteropathica: Infants, Children, and Adolescents: Oral: 3 mg/kg/day
腎功能調整劑量
There are no dosage adjustments provided in the manufacturer’s labeling.
肝功能調整劑量
There are no dosage adjustments provided in the manufacturer’s labeling.