公費疫苗 COVID-19 Prevention in persons ≥18 years of age (仿單連結)
藥理
Vaccine, Adenovirus Vector
藥動學
禁忌症
1. History of a severe allergic reaction (eg, anaphylaxis) after a previous dose or to a component of the formulation 2. History of immediate allergic reaction (regardless of severity and occurring within 4 hours) to a previous dose 3. Known allergy to any component of the formulation (eg, polysorbate 80) 4. Major venous and/or arterial thrombosis with thrombocytopenia following previous dose of AstraZeneca COVID-19 Vaccine or Covishield 5. History of capillary leak syndrome
懷孕分類
正在哺乳、可能懷孕或有計畫懷孕之女性,皆應評估接種之利益與風險。
哺乳分類
It is not known if components of adenovirus vector vaccine are present in breast milk.
副作用
Common: Nausea, pain/tenderness/warm sensation at injection site, chills, fatigue, headache, malaise, arthralgia, myalgia, fever Post-authorization: 1. Cardiovascular: Arterial thrombosis, capillary leak syndrome, portal vein thrombosis, pulmonary embolism, thrombosis 2. Hematologic & oncologic: Disseminated intravascular coagulation, thrombocytopenia (in combination with thrombosis; also referred to as vaccine-induced [VITT]) 3. Nervous system: Cerebral hemorrhage, cerebral sinus thrombosis, Guillain-Barre syndrome
劑量和給藥方法
IM 0.5 mL per dose for 2 doses administered 28 to 84 days (4 to 12 weeks) apart
小兒調整劑量
腎功能調整劑量
There are no dosage adjustments provided in the manufacturer's labeling.
肝功能調整劑量
There are no dosage adjustments provided in the manufacturer's labeling.