藥碼
NIM01
藥名
Cisatracurium 2 mg/mL, 5 mL/amp
英文商品名
Nimbex 針 麻醉 10 mg/5 mL/Amp
中文商品名
肌弛適注射液
螢幕名
Nimbex 針 麻醉 10 mg/5 mL/Amp
劑型
Inj
規格
Inj 10 mg/ 5 ml/ Amp, 5 Amps/ box
成分
藥理分類
Autonomic-Neuromuscular Blocking Agents
健保碼
BC22770221
ATC碼
適應症
|
【缺藥訊息】 公告日期：2022/11/24。 缺藥品項：Nimbex 針 麻醉 10mg/5mL/Amp。 缺藥原因：原料問題導致缺藥。 替代藥品：國內無同成份規格替代品。 配套措施：採購同類替代品 (Atracurium 針 25mg/2.5mL)，缺貨品項庫存量用罄關檔停用，替代品預計於 2022/11/25 到貨 (依照實際到貨日為準)。 #建議持續輸注 (IV pump) 之高警訊藥品 |
Neuromuscular blockade for endotracheal intubation, surgery, or mechanical ventilation
藥理
Neuromuscular Blocker Agent
Blocks neural transmission at the myoneural junction by binding with cholinergic receptor sites
Blocks neural transmission at the myoneural junction by binding with cholinergic receptor sites
藥動學
1. Onset: 2-3 min; peak effect: 3-5 min
2. Duration: 31-91 min
3. Metabolism: undergoes rapid non-enzymatic degradation in the blood stream, additional metabolism occurs via ester hydrolysis; some active metabolites
4. Elimination half-life: 22-29 min
2. Duration: 31-91 min
3. Metabolism: undergoes rapid non-enzymatic degradation in the blood stream, additional metabolism occurs via ester hydrolysis; some active metabolites
4. Elimination half-life: 22-29 min
禁忌症
Hypersensitive to cisatracurium, atracurium or benzenesulfonic acid
懷孕分類
B
哺乳分類
No data available
副作用
Hypotension, bradycardia, flushing, rush, pruritus, bronchospasm
劑量和給藥方法
Dosage:
1. Intubating dose: Initial 0.15–0.2 mg/kg IV bolus, then 0.03 mg/kg IV 40-60 min after initial dose
2. Continuous IV infusion: initial 1–3 μg/kg/min, then 1–2 μg/kg/min
Administration:
1. Mix in D5W, NS or D5NS, do NOT dilute in LR
2. Not to be used IM
1. Intubating dose: Initial 0.15–0.2 mg/kg IV bolus, then 0.03 mg/kg IV 40-60 min after initial dose
2. Continuous IV infusion: initial 1–3 μg/kg/min, then 1–2 μg/kg/min
Administration:
1. Mix in D5W, NS or D5NS, do NOT dilute in LR
2. Not to be used IM
小兒調整劑量
(For children 2-12 years of age)
1. Initial: 0.1 mg/kg IV over 5-10 seconds
2. Maintenance: initial 3 μg/kg/min IV infusion, then decrease to 1-2 μg/kg/min
1. Initial: 0.1 mg/kg IV over 5-10 seconds
2. Maintenance: initial 3 μg/kg/min IV infusion, then decrease to 1-2 μg/kg/min
腎功能調整劑量
There are no dosage adjustments provided in the manufacturer’s labeling.
肝功能調整劑量
There are no dosage adjustments provided in the manufacturer’s labeling.
安定性
Should be refrigerated at 2-8℃ and protected from light
注射給藥指引
給藥途徑
IV pump
靜脈輸注液
D5W、 NS
每瓶稀釋液體積
-
注射濃度
0.1 mg/mL (micromedex)
給藥速率
詳見「劑量和給藥方法」
安定性
Should be refrigerated at 2-8℃ and protected from light
注意事項
相容：
amiodarone, bumetanide, calcium gluconate, dexmedetomidine, diltiazem, dobutamine, dopamine, epinephrine, esmolol, heparin, ketamin, lansoprazole, lidocaine, lorazepam, magnesium sulfate, mannitol, midazolam, milrinone, morphine, nicardipine, nitroglycerin, norepinephrine, octreotide, sodium bicarbonate, vasopressin
不相容：pantoloc, potassium chloride, propofol
完整資訊請見重症常用藥品靜脈相容性表
amiodarone, bumetanide, calcium gluconate, dexmedetomidine, diltiazem, dobutamine, dopamine, epinephrine, esmolol, heparin, ketamin, lansoprazole, lidocaine, lorazepam, magnesium sulfate, mannitol, midazolam, milrinone, morphine, nicardipine, nitroglycerin, norepinephrine, octreotide, sodium bicarbonate, vasopressin
不相容：pantoloc, potassium chloride, propofol
完整資訊請見重症常用藥品靜脈相容性表
藥袋資訊
臨床用途
高選擇性及競爭性的非去極化神經肌肉阻斷劑麻醉劑與插管之輔助劑
主要副作用
心搏徐緩、支氣管痙攣、低血壓、面潮紅、肌肉病變。
泡製方法
儲存方式
請置於 2-8℃ 冷藏儲存
注意事項
其他說明
單位常備藥，門診藥局不備庫 | 藥庫 冰X13
藥品外觀
顏色
形狀
剝痕
標記1
標記2
其他
健保藥價
73
自費價
97.09
仿單
資料庫
健保給付規定