1. Absorption: Low systemic absorption 2. Half-life elimination: ~3 hours 3. Excretion: Urine (60% to 70%, mostly as unchanged drug)
禁忌症
Hypersensitivity to olopatadine hydrochloride or any component of the formulation.
懷孕分類
Olopatadine has minimal systemic absorption following ophthalmic administration. Systemic absorption would be required in order for olopatadine to cross the placenta and reach the fetus.
哺乳分類
It is not known if olopatadine (ophthalmic) is excreted in breast milk. The manufacturer recommends that caution be exercised when administering olopatadine (ophthalmic) to nursing women.
副作用
Cold symptoms (?10%), Pharyngitis (?10%), abnormal sensation in eyes (2% to 5%), blurred vision (2% to 5%), dry eye syndrome (2% to 5%), superficial punctate keratitis (2% to 5%), dysgeusia (2% to 5%)
劑量和給藥方法
Instill 1 drop into each affected eye twice daily (allowing 6 to 8 hours between doses).
小兒調整劑量
Children ?2 years and Adolescents: Instill 1 drop into affected eye(s) twice daily, allowing 6 to 8 hours between doses.
腎功能調整劑量
There are no dosage adjustments provided in the manufacturer’s labeling.
肝功能調整劑量
There are no dosage adjustments provided in the manufacturer’s labeling.