Open-angle glaucoma, lowering of intraocular pressure

1. Brinzolamide: carbonic anhydrase inhibitors
2. Brimonidine: sympathomimetics

Excretion
Renal

Allergic to sulphonamides. Severe renal function.

C/B

Infant risk cannot be ruled out.

Gastrointestinal: Dysgeusia (3% to 5%), xerostomia (3% to 5%) Hypersensitivity: Local ocular hypersensitivity reaction (3% to 5%) Ophthalmic: Blurred vision (3% to 5%), eye irritation (3% to 5%)

Adults: 1 drop bid

Not recommended for children under 18 y/o.

No data in patient with severe renal function ([CrCl] < 30 ml/min), avoid using.

No data in liver impairment population. Use with caution.

store below 30 °C. Protect from moisture and light.