眼用抗感染 Ocular infections: Treatment of external infections of the eye and its adnexa caused by susceptible bacteria.
藥理
Interferes with bacterial protein synthesis by binding to 30S ribosomal subunit resulting in a defective bacterial cell membrane
藥動學
Absorption: Systemic absorption: Undetectable (<0.2 mcg/mL) (Filatov 1994); tear film exposure and time above MIC90 are significantly greater with viscous ophthalmic solution.
禁忌症
Hypersensitivity to tobramycin or any component of the formulation
懷孕分類
B
哺乳分類
The amount of tobramycin available systemically following topical application of the ophthalmic drops is undetectable
Apply half-inch ribbon into affected eye(s) 2 or 3 times daily for mild to moderate infections; for severe infections, apply every 3 to 4 hours until improvement